Medical Research Insights - MRIs

Medical Research Insights - MRIs Curated Medical Research Insights (MRIs) [daily]

Scientists have successfully identified a gene key to colon cancer and discovered one possible way the environment aroun...
10/21/2022

Scientists have successfully identified a gene key to colon cancer and discovered one possible way the environment around a colon cancer tumor can trigger malignant growth; via

Genetic evidence shows that targeting PDZK1IP1 inhibits tumors....

As pharma companies shift from developing drugs that serve large populations to specialty drugs, targeting the right pat...
10/05/2022

As pharma companies shift from developing drugs that serve large populations to specialty drugs, targeting the right patients becomes a key driver of success. Analyzing patient-level real-world data is essential for the successful launch and management of new products.

By Carolyn Zele, Advisor, Solution Consulting, MMIT, and Lance Wolkenbrod, Senior Director, Commercial Solutions, Panalgo | Despite investing heavily in the right data and analytics to inform their commercial strategy, many pharma companies do no...

As CAR T-cell products become more important in the fight against diseases, the FDA is making new recommendations for CA...
10/05/2022

As CAR T-cell products become more important in the fight against diseases, the FDA is making new recommendations for CAR T-cell developers. Our own David Perez-Caballero, Ph.D., talks to Genetic Engineering & Biotechnology News about the new guidance.

A CRO summarizes the FDA’s recommendations for developers and highlights issues that have been raised in public comments....

Cancer cells will stop at nothing to grow—right down to deleting sections of their DNA that contain growth suppression g...
09/30/2022

Cancer cells will stop at nothing to grow—right down to deleting sections of their DNA that contain growth suppression genes. | Pinning down backup genes along with the metabolic pathways they’re regulating, has historically required tedious screenings that gave limited information about how different genes interact. Now, a team of researchers has used machine learning to streamline the process and add context that could make precision medicines more precise.

Cancer cells will stop at nothing to grow—right down to deleting sections of their DNA that contain growth suppression genes. | Pinning down backup genes along with the metabolic pathways they’re regulating, has historically required tedious scree...

Researchers from King’s College London and The Institute of Cancer Research, London, have identified immune cell types t...
09/30/2022

Researchers from King’s College London and The Institute of Cancer Research, London, have identified immune cell types that could be targeted to develop specific immunotherapies for patients whose cancer failed to respond to chemotherapy.

Several cell types that worth investigating further were identified to understand how they interact with resistant cancer cells....

An program developed by researchers at Stanford calculated measurements more accurately than those performed by human ...
09/09/2022

An program developed by researchers at Stanford calculated measurements more accurately than those performed by human clinicians in the trial.

An artificial intelligence program developed by researchers at Stanford University was able to streamline ultrasound exams of the heart—to the point where trained cardiologists couldn’t tell whethe | An artificial intelligence program developed by...

The pandemic brought to the forefront of public awareness. Now there are huge opportunities for growth and innovatio...
09/09/2022

The pandemic brought to the forefront of public awareness. Now there are huge opportunities for growth and innovation across the industry.

Manohara B Halasiddappa...

Half of all patients are children, and — out of desperation to find a cure — more and more families are forming their ...
09/07/2022

Half of all patients are children, and — out of desperation to find a cure — more and more families are forming their own foundations to grow funds for research.

Families are forming their own businesses to find treatments for ultra-rare diseases that affect fewer than 1,000 patients, territory many drugmakers deem too risky....

Although and are hot buzz words in science today, much more work could be done in applying these techniques to biopr...
09/07/2022

Although and are hot buzz words in science today, much more work could be done in applying these techniques to bioprocessing. GEN speaks to an expert who sees 3 major benefits. Read more:

Using AI/ML-based surrogates to digitally mimic the real system leads to the reduction of resources and accelerates the process development timeline....

Researchers have found that increasing a genetic quirk can boost beta amyloid clearance, holding the potential to help p...
09/04/2022

Researchers have found that increasing a genetic quirk can boost beta amyloid clearance, holding the potential to help prevent Alzheimer’s.

Scientists have discovered a new druggable pathway that may boost beta amyloid clearance, holding the potential to be used to help prevent Alzheimer’s dementia in humans. | Scientists have discovered a new druggable pathway that may boost beta amy...

It’s the 20th year Fierce Biotech sought out the most innovative private biotechs, so now they are checking in on past h...
09/04/2022

It’s the 20th year Fierce Biotech sought out the most innovative private biotechs, so now they are checking in on past honorees.

It’s the 20th year we’ve sought out the most innovative private biotechs, which also means we've entered the second decade of checking in on our past honorees. In 2012, we profiled the biggest risk takers in biotech, narrowing our list down to 1...

FDA Commissioner Robert Califf says the industry and researchers should redouble its efforts to treat common chronic d...
09/03/2022

FDA Commissioner Robert Califf says the industry and researchers should redouble its efforts to treat common chronic diseases and addiction. Read up on his new editorial article.

FDA Commissioner Robert Califf, M.D., has often been blunt and direct when outlining his goals and aspirations for the FDA since taking the helm for the second time earlier this year. | FDA Commissioner Robert Califf says the biopharma industry a...

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